OpenAI’s specialized biological AI model did not simply redesign proteins, it optimized their form with extraordinary precision. Working with Retro Bio, researchers trained a GPT-4b micro system on biological data rather than text, enabling it to re-engineer Yamanaka factors, the proteins known to reprogram adult cells into stem cells. In their original 2012 discovery, these factors converted less than 0.1 percent of cells over several weeks. The new AI-designed versions achieved success rates a