It's Friday, July 25 and the Cubs (60-42) are in Chicago to take on the White Sox (37-66). Shota Imanaga is slated to take the mound for Chicago against Adrian Houser for Chicago. The Cubs are 1-3 in the past four games and coming off a series loss to the Royals where they dropped two of three.

The Chicago Cubs (60-42) visit the South Side of Chicago to face the Chicago White Sox (37-66) Friday in the first game of a 3-game interleague series. First pitch from Rate Field is at 7:40 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Cubs vs. White Sox odds and make our expert MLB picks and predictions for the best bets.

The Cubs ’ lineup had a bit of a different look Friday against White Sox right-hander Adrian Houser, who is in the midst of the best season of his career. Switch-hitting Vidal Brujan got the start at third base over Matt Shaw, and left-handed-hitting Reese McGuire started behind the plate.