Semaglutide at a dose of 2.4 mg has established weight-loss and cardiovascular benefits, and cagrilintide at a dose of 2.4 mg ...

In previous treat-to-target trials, adjustments to the dose of basal insulin have been made at least weekly, according to ...

One of the more difficult decisions for patients with poorly controlled type 2 diabetes, as well as for their clinicians, is when to add or switch to daily insulin therapy. Initiation of ...

Intracranial aneurysms are common, and the risk of rupture is influenced by size, location, morphology, and factors such as ...

This review considers enteral nutrition in the context of disease-related malnutrition, provides evidence for the use of enteral nutrition in hospitalized patients, and discusses practice considera ...

Case Records of the Massachusetts General Hospital from The New England Journal of Medicine — A 56-Year-Old Woman with Sore Throat and Rash ...

Chronic obstructive pulmonary disease (COPD) is characterized by the progressive development of airflow limitation that is not fully reversible. 1 The term COPD encompasses chronic obstructive ...

In this phase 3 trial, we randomly assigned patients with pulmonary arterial hypertension (WHO functional class III or IV) and a high 1-year risk of death (Registry to Evaluate Early and Long-Term ...

Chronic spontaneous urticaria is an idiopathic syndrome defined by recurring itch, hives, or angioedema (or a combination of these symptoms) for more than 6 weeks. Remibrutinib, an oral, highly sel ...

We conducted a double-blind, controlled clinical trial to evaluate the safety, side-effect profile, and efficacy of immunization, by means of mosquito bites, with a second-generation genetically ...

Hairy-cell leukemia, a rare B-cell cancer driven by a BRAF mutation and manifesting with cytopenias and splenomegaly, is responsive to purine analogue chemotherapy and to BRAF inhibitors combined w ...

Primary central nervous system (CNS) vasculitis, also known as primary angiitis of the CNS, is a rare form of vasculitis that is limited to the brain and spinal cord and causes a variety of ...