BACKGROUND: Penetrance and risk of ventricular arrhythmias (VAs) in arrhythmogenic right ventricular cardiomyopathy (ARVC) are increasingly recognized as being genotype specific. Therefore, ...

Background: Major noncardiac surgery carries high rates of postoperative myocardial injury and other complications. Remote ischemic preconditioning (RIPC) was reported to decrease these complications.

Food plays important roles in communities through social cohesion, community development, and food justice and equity. 9 Food also plays important roles in identity, reflects cultural heritage and ...

In this study, we report the cardioprotective effect of a recently described pan-ERR agonist SLU-PP-332 (332) 21 and another structurally distinct pan-ERR agonist SLU-PP-915 (915) in pressure overload ...

COVID-19 is characterized by dysregulated thrombosis and coagulation that can increase mortality in patients. Platelets are fast responders to pathogen presence, alerting the surrounding immune cells ...

Perioperative stroke, defined as a cerebrovascular event occurring during surgery or within 30 days postoperatively, remains a devastating complication associated with substantial morbidity, ...

BACKGROUND: Cardiac amyloidosis is associated with poor outcomes and is caused by the interstitial deposition of misfolded proteins, typically ATTR (transthyretin) or AL (light chains). Although ...

BACKGROUND: Pulmonary artery endothelial cell (PAEC) dysfunction is a pathological hallmark of pulmonary hypertension (PH). Yet, the roles of long noncoding RNAs (lncRNAs) driven by super-enhancers ...

The change in 6MWD after SGLT2i in patients with acquired HF has been mixed. In patients with HF and preserved EF randomized to dapagliflozin versus placebo, the baseline mean 6MWD was only 249±113 m, ...

A recent study grouped 155 patients with HF who completed cardiac rehabilitation with supervised exercise training into those who had an improvement in peak rate of oxygen uptake (V̇O 2Peak) (>6% ...

Background: Many individuals with chronic kidney disease (CKD) face considerable but modifiable risk of cardiovascular and renal outcomes due to suboptimal implementation of guideline-directed medical ...

Response by Campo and Pavasini to Letter Regarding Article, “Complete Versus Culprit-Only Revascularization in Older Patients With ST-Segment–Elevation Myocardial Infarction: An Individual Patient ...