Background Liver metastasis is a major cause of mortality in patients with colorectal cancer (CRC). Understanding how CRC cells influence the formation of hepatic premetastatic niches (PMNs) is ...

Background Metabolic dysfunction-associated steatotic liver disease (MASLD) affects over 30% of the general population and is ...

The British Society of Gastroenterology’s (BSG) latest 5-year national guideline for inflammatory bowel disease (IBD)1 has recently completed. This adjunct commentary to the guideline contains the ...

Introduction Iron deficiency anaemia (IDA) is common with BSG guidance suggesting Gastrointestinal (GI) blood loss from colonic or gastric cancer, and malabsorption in coeliac disease are the most ...

BACKGROUND Use of the conventional Western and Japanese classification systems of gastrointestinal epithelial neoplasia results in large differences among pathologists in the diagnosis of oesophageal, ...

Knowledge on SARS-CoV-2 infection and its resultant COVID-19 in liver diseases has rapidly increased during the pandemic. Hereby, we review COVID-19 liver manifestations and pathophysiological aspects ...

Objective IBD therapies and treatments are evolving to deeper levels of remission. Molecular measures of disease may augment current endpoints including the potential for less invasive assessments.

BACKGROUND AND AIMS Gastric metaplasia is frequently seen in biopsies of the duodenal cap, particularly when inflamed or ulcerated. In its initial manifestation small patches of gastric foveolar cells ...

Background and aims Conventional hot snare endoscopic mucosal resection (H-EMR) is effective for the management of large (≥20 mm) non-pedunculated colon polyps (LNPCPs) however, electrocautery-related ...

Background Hepatocellular carcinoma (HCC) is the sixth most common cancer and the fourth leading cause of cancer-related death worldwide. Effective early diagnosis is hampered by the lack of ...

Background Orthotopic liver transplantation is indicated in patients with end-stage liver disease, hepatocellular carcinoma (HCC) within transplant criteria and acute fulminant hepatic failure.

Results We found that high intrahepatic uric acid contents were positively related to GSDMD-mediated pyroptosis in NASH mice (IDDF2024-ABS-0226 Figure 1. Intrahepatic uric acid is associated with ...