Tissue microarrays (TMAs) have become a mainstay in preclinical and translational research, especially for the development of biomarker assays for characterization of disease.

Tissue microarrays application in non-small cell lung carcinoma: Morphometric study of immunohistochemical expression of topoisomerase IIa correlating with molecular detection of the specific gene ...

Other TMA Applications for Assay Validation Tissue analytes are differentially susceptible to preanalytical variables that affect tissue-based assays.

Emphasis on Potential Clinical Applications and Enhancing RNA Sample Quality Researchers are beginning to look at tissue microarrays (TMA) from different perspectives, including one with a strong ...

This review summarizes our current experience with this field, discusses technical issues for tissue microarray construction, and indicates opportunities and limitations for their application.

Image: Courtesy of Biocat SCORES OF CORES: Each tissue core on this microarray provides another datapoint that helps researchers better define the molecular characteristics of interesting genes. In ...

The main application of microarrays is gene expression analysis, but other uses for these arrays continue to grow in popularity. Laura Bonetta reports on the use of this technology to analyze ...

Abbreviations: TMA, tissue microarray; FISH, fluorescent in situ hybridization. In this article, we provide a set of evidence-based guidelines (summarized in Table 2) for array construction. The ...

OpTMA allows the user to dearray entire tissue microarrays with one click, build virtual, patient-centric biomarker arrays from real arrays, and carry out rapid assessment of biomarker panel ...

Precision for Medicine offers an extensive inventory of pathologist-reviewed FFPE tissue blocks, slides, curls, cores, and tissue microarrays from both normal and diseased subjects, all collected ...

Application of the reverse phase protein microarray (RPPA) Reverse phase protein microarrays (RPPA) provide a method for application on pure protein lysates isolated from tissue or cultured cells.