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A new AI tool reveals how tangled DNA knots impact health and disease, offering insights for drug discovery and genetic ...
A) DNA polymerase binds to a single-stranded DNA template (blue) and synthesizes a complementary strand of DNA (red). B) When DNA polymerase randomly incorporates a fluorescently labeled ddNTP ...
NGS relies on sequencing by synthesis: the sequence of a template DNA strand is determined by synthesizing a complementary strand from fluorescently labeled bases.
By creating a more true-to-life representation of DNA's environment, researchers at Northwestern University have discovered that strand separation - the essential process a "resting" double helix ...
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