Outside of Jackson State's pandemic-shortened spring season in 2021, Sanders has never coached college football without his sons -- Shedeur and Shilo -- on his roster. Shedeur was drafted in the fifth round by the Cleveland Browns, while Shilo signed a free agent contract with the Tampa Bay Buccaneers.

Deion Sanders was diagnosed with a “high-risk” form of bladder cancer earlier this year, and is now cancer-free after having his bladder removed, he and his doctors revealed Monday.

Deion Sanders already has a victory under his belt in 2025. The CU Buffs football coach announced he beat bladder cancer.